PrimePCR™ ddPCR™ Expression Probe Assay: Dclk1, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCIP0034291; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5119903
Chromosome Location:   3:55256159-55380867question
Amplicon Length:   110

Gene Information

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains which bind microtubules and regulate microtubule polymerization a C-terminal serine/threonine protein kinase domain which shows substantial homology to Ca2+/calmodulin-dependent protein kinase and a serine/proline-rich domain in between the doublecortin and the protein kinase domains which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes including neuronal migration retrograde transport neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been found but the biological validity of some variants has not been determined. These variants encode different isoforms which are differentially expressed and have different kinase activities. [provided by RefSeq Sep 2010]

Gene Symbol:   Dclk1
Gene Name:   Doublecortin-like kinase 1
Aliases:   1700113D08Rik, 2810480F11Rik, AI836758, Click-I, Cpg16, Dcamkl1, Dcl, Dclk, mKIAA0369
RefSeq:   NC_000069.6 NT_039240.8
Ensembl:   ENSMUSG00000027797
Entrez:   13175
UniGene:   Mm.393242
Chromosome Mapping:   3|3 D

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