This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qMmuCIP0030122; Intron-spanning
This gene encodes a protein which binds to the SH3 domain of the Yes proto-oncogene product a tyrosine kinase. This protein contains a WW domain consisting of four conserved aromatic amino acids including two tryptophan residues. This conserved WW domain is found in various structural regulatory and signaling molecules in various species and may play a role in protein-protein interaction. Following cellular damage phosphorylation of this encoded protein may suppress apoptosis. This protein may be involved in malignant transformation in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq Jan 2010]