PrimePCR™ ddPCR™ Expression Probe Assay: Trp63, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCIP0030077; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5112619
Chromosome Location:   16:25868172-25871065question
Amplicon Length:   117

Gene Information

This gene encodes tumor protein p63 a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53 p63 and p73 which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues such as teeth and mammary glands which develop as a result of interactions between mesenchyme and epithelium. Both alternative splicing and the use of alternative promoters result in multiple transcript variants encoding different protein isoforms.[provided by RefSeq Dec 2009]

Gene Symbol:   Trp63
Gene Name:   Transformation related protein 63
Aliases:   AI462811, Ket, P51/P63, P63, P73l, Tp63, Trp53rp1
RefSeq:   NC_000082.6 NT_039624.8
Ensembl:   ENSMUSG00000022510
Entrez:   22061
UniGene:   Mm.20894
Chromosome Mapping:   16 B1|16 19.3 cM

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