PrimePCR™ ddPCR™ Expression Probe Assay: Mfrp, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCIP0029135; Intron-spanning

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5110903
Chromosome Location:   9:44103700-44104702question
Amplicon Length:   163

Gene Information

The protein encoded by this gene contains a region with similarity to the cysteine-rich domain (CRD) of frizzled a gene originally found in Drosophila that controls tissue polarity. This protein functions in eye development where it is necessary for the maintenance of photoreceptor outer segments. Mutations in this gene cause retinal degeneration 6 in mice which gives rise to a mouse model for human retinitis punctata albescens. Bicistronic transcripts composed of the coding sequences for this gene (Mfrp) and the C1q and tumor necrosis factor related protein 5 gene (C1qtnf5) have been identified and the resulting products can interact with each other. Co-transcription of C1qtnf5 and Mfrp has been observed in both human and mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq Jun 2010]

Gene Symbol:   Mfrp
Gene Name:   Membrane-type frizzled-related protein
Aliases:   rd6
RefSeq:   NC_000075.6 NT_039472.8
Ensembl:   ENSMUSG00000034739
Entrez:   259172
UniGene:   Not Available
Chromosome Mapping:   9 A5.1|9 25.5 cM

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