PrimePCR™ ddPCR™ Expression Probe Assay: Ces2c, Mouse

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCIP0028867; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5110410
Chromosome Location:   8:104847093-104848058question
Amplicon Length:   156

Gene Information

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics such as cocaine and heroin and endogenous substrates with ester thioester or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. The transcription of this gene is regulated by several factors including HNF-4alpha (hepatocyte nuclear factor-4alpha) Sp1 (specificity protein 1) Sp3 and USF1 (upstream stimulatory factor 1). The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with several family members including a few of pseudogenes and Ces5 on chromosome 8.[provided by RefSeq Jun 2010]

Gene Symbol:   Ces2c
Gene Name:   Carboxylesterase 2C
Aliases:   Ces2, ces2A3
RefSeq:   NC_000074.6 NT_078575.7
Ensembl:   ENSMUSG00000061825
Entrez:   234671
UniGene:   Mm.28191
Chromosome Mapping:   8 D3|8

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