PrimePCR™ ddPCR™ Expression Probe Assay: Chrne, Mouse

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCIP0028572; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5109880
Chromosome Location:   11:70615736-70617029question
Amplicon Length:   85

Gene Information

This gene encodes the epsilon subunit of the muscle-derived nicotinic acetylcholine receptor a pentameric neurotransmitter receptor and member of the ligand-gated ion channel superfamily. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. In mice deficiency of this gene can lead to a decline in the number of nicotinic acetylcholine receptors at neuromuscular junctions and causes progressive muscle weakness atrophy and premature death. Mutations in this gene serve as a pathophysiological model for human congenital myasthenia. Several alternatively spliced transcript variants of this gene have been described but their full-length nature is not known. [provided by RefSeq Nov 2012]

Gene Symbol:   Chrne
Gene Name:   Cholinergic receptor, nicotinic, epsilon polypeptide
Aliases:   Acre
RefSeq:   NC_000077.6 NT_096135.6 NT_187026.1
Ensembl:   ENSMUSG00000014609
Entrez:   11448
UniGene:   Mm.4980
Chromosome Mapping:   11 B3|11 42.0 cM

Number Description Download
10033487 ddPCR™ Mutation Detection Assays Product Insert, Ver C Click to download
10033173 ddPCR™ Copy Number Variation Assays Product Insert, Ver C Click to download
10041702 PrimePCR™ ddPCR™ Gene Expression Assays (EvaGreen) Product Insert, Rev A Click to download
10047489 ddPCR™ Mutation Detection Assays Product Insert, Ver B Click to download
10048730 PrimePCR™ ddPCR™ Gene Expression Probe Assays Product Insert, Rev A Click to download