PrimePCR™ ddPCR™ Expression Probe Assay: Txnrd3, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCEP0062142; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5107913
Chromosome Location:   6:89651593-89654139question
Amplicon Length:   72

Gene Information

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin but unlike other mammalian thioredoxin reductases (TRs) it contains an additional glutaredoxin domain and shows highest expression in testes. Like other TRs it contains a C-terminal penultimate selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure the sec insertion sequence (SECIS) which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG leading to additional isoforms. [provided by RefSeq May 2010]

Gene Symbol:   Txnrd3
Gene Name:   Thioredoxin reductase 3
Aliases:   AI196535, TR2, Tgr
RefSeq:   NC_000072.6 NT_039353.8
Ensembl:   ENSMUSG00000000811
Entrez:   232223
UniGene:   Mm.229332
Chromosome Mapping:   6 D1|6

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