PrimePCR™ ddPCR™ Expression Probe Assay: Gpx4, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0060653; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5107670
Chromosome Location:   10:80056207-80056331question
Amplicon Length:   95

Gene Information

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide organic hydroperoxide and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation rat produces proteins that localize to the nucleus mitochondrion and cytoplasm. In mice experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. Two pseudogenes exist for this gene one on chromosome 10 and one on chromosome 17. [provided by RefSeq Jul 2008]

Gene Symbol:   Gpx4
Gene Name:   Glutathione peroxidase 4
Aliases:   1700027O09Rik, PHGPx, mtPHGPx, snGPx
RefSeq:   NC_000076.6 NT_039500.8
Ensembl:   ENSMUSG00000075706
Entrez:   625249
UniGene:   Mm.359573
Chromosome Mapping:   10 C1|10 43.0 cM

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