PrimePCR™ ddPCR™ Expression Probe Assay: Ano5, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0058023; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5102686
Chromosome Location:   7:51598395-51598519question
Amplicon Length:   95

Gene Information

This gene encodes a member of the anoctamin family which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels this protein is reported to have little anion conductance activity. Elevated levels of this protein were found in dystrophic mice. In humans mutations of this gene are associated with with musculoskeletal disorders such as myopathies muscular dystrophy and gnathodiaphyseal dysplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq Dec 2012]

Gene Symbol:   Ano5
Gene Name:   Anoctamin 5
Aliases:   9330162L24, Gdd1, Tmem16e
RefSeq:   NC_000073.6 NT_187035.1
Ensembl:   ENSMUSG00000055489
Entrez:   233246
UniGene:   Mm.254431
Chromosome Mapping:   7 B5|7

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