PrimePCR™ ddPCR™ Expression Probe Assay: Tap1, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0057739; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5102164
Chromosome Location:   17:34191336-34191476question
Amplicon Length:   111

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This protein forms a heterodimer with Tap2 that transports short peptides from the cytosol into the endoplasmic reticulum lumen. Mutations in the human gene may be associated with ankylosing spondylitis insulin-dependent diabetes mellitus and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jun 2009]

Gene Symbol:   Tap1
Gene Name:   Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Aliases:   ABC17, APT1, Abcb2, Ham-1, Ham1, MTP1, PSF1, RING4, TAP, Tap-1, Y3
RefSeq:   NC_000083.6 NT_039649.8 NT_039662.3 NT_187004.1 NT_187027.1
Ensembl:   ENSMUSG00000037321
Entrez:   21354
UniGene:   Mm.482076
Chromosome Mapping:   17 B1|17 18.6 cM

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