PrimePCR™ ddPCR™ Expression Probe Assay: Cftr, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCEP0056740; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5100379
Chromosome Location:   6:18225942-18226075question
Amplicon Length:   104

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This gene encodes the cystic fibrosis transmembrane regulator and a chloride channel that controls the regulation of other transport pathways. Mutations in this gene have been associated with autosomal recessive disorders such as cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternative splicing of exons 4 5 and 11 have been observed but full-length transcripts have not yet been fully described. [provided by RefSeq Jul 2008]

Gene Symbol:   Cftr
Gene Name:   Cystic fibrosis transmembrane conductance regulator homolog
Aliases:   AW495489, Abcc7
RefSeq:   NC_000072.6 NT_039340.7
Ensembl:   ENSMUSG00000041301
Entrez:   12638
UniGene:   Mm.15621
Chromosome Mapping:   6 A3|6 3.1 cM

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