PrimePCR™ ddPCR™ Expression Probe Assay: Gria2, Mouse

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCEP0055524; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5098053
Chromosome Location:   3:80707121-80707699question
Amplicon Length:   109

Gene Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) and function as ligand-activated cation channels. These channels are assembled from 4 related subunits Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain which is thought to render the channel impermeable to Ca(2+). Alternative splicing resulting in transcript variants encoding different isoforms (including the flip and flop isoforms that vary in their signal transduction properties) has been noted for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   Gria2
Gene Name:   Glutamate receptor, ionotropic, AMPA2 (alpha 2)
Aliases:   GluA2, GluR-B, Glur-2, Glur2
RefSeq:   NC_000069.6 NT_039240.8
Ensembl:   ENSMUSG00000033981
Entrez:   14800
UniGene:   Mm.220224
Chromosome Mapping:   3 E3|3 33.6 cM

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