PrimePCR™ ddPCR™ Expression Probe Assay: Ptges2, Mouse

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCEP0054962; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5096979
Chromosome Location:   2:32396022-32396111question
Amplicon Length:   60

Gene Information

The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE) possibly via an interaction with CAAAT/enhancer-binding protein-beta. [provided by RefSeq Oct 2009]

Gene Symbol:   Ptges2
Gene Name:   Prostaglandin E synthase 2
Aliases:   0610038H10Rik, C79137, Gbf1, Mpges2, Pges2
RefSeq:   NC_000068.7 NT_039206.8
Ensembl:   ENSMUSG00000026820
Entrez:   96979
UniGene:   Mm.28048
Chromosome Mapping:   2 B|2

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