PrimePCR™ ddPCR™ Expression Probe Assay: Cldn1, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0054007; exonic

Fluorophore:   FAM
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5095192
Chromosome Location:   16:26358909-26359017question
Amplicon Length:   79

Gene Information

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. The knockout mice lacking this gene die soon after birth as a consequence of dehydration from trandermal water loss indicating that this gene is indispensable for creating and maintaining the epidermal barrier. The protein encoded by this gene also has gastric tumor suppressive activity and is a key factor for hepatitis C virus (HCV) entry. [provided by RefSeq Aug 2010]

Gene Symbol:   Cldn1
Gene Name:   Claudin 1
Aliases:   AI596271
RefSeq:   NC_000082.6 NT_039624.8
Ensembl:   ENSMUSG00000022512
Entrez:   12737
UniGene:   Mm.289441
Chromosome Mapping:   16 B2|16

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