PrimePCR™ ddPCR™ Expression Probe Assay: Fgfr3, Mouse

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0042662; exonic

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5091444
Chromosome Location:   5:33729735-33729847question
Amplicon Length:   83

Gene Information

This gene encodes a member of the fibroblast growth factor receptor family. Members of this family are highly conserved proteins that differ from one another in their ligand affinities and tissue distribution. A representative protein consists of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation. This family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene may be associated with craniosynostosis and multiple types of skeletal dysplasia. A pseudogene of this gene is located on chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Apr 2011]

Gene Symbol:   Fgfr3
Gene Name:   Fibroblast growth factor receptor 3
Aliases:   CD333, FR3, Fgfr-3, Flg-2, HBGFR, Mfr3, sam3
RefSeq:   NC_000071.6 NT_039305.8
Ensembl:   ENSMUSG00000054252
Entrez:   14184
UniGene:   Mm.6904
Chromosome Mapping:   5 B|5 20.0 cM

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