PrimePCR™ ddPCR™ Expression Probe Assay: Vkorc1, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0036488; Exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5089856
Chromosome Location:   7:127895481-127895617question
Amplicon Length:   107

Gene Information

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 23-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin and it is the product of this gene that is sensitive to warfarin. In humans mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and in humans and rats with warfarin resistance. [provided by RefSeq Jul 2008]

Gene Symbol:   Vkorc1
Gene Name:   Vitamin K epoxide reductase complex subunit 1
Aliases:   D7Wsu86e
RefSeq:   NC_000073.6 NT_039433.8
Ensembl:   ENSMUSG00000096145
Entrez:   27973
UniGene:   Mm.29703
Chromosome Mapping:   7 F3|7 61.0 cM

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