PrimePCR™ ddPCR™ Mutation Assay:MYD88 p.L265P, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for mutation detection. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   65nt amplicon; crosses exon-intron junction; in silico

 
Fluorophore:   FAM
List Price:    $325.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Mutation Detection in silico design
Unique Assay ID:   dHsaIS2506944
Chromosome Location:   3:38182580-38182702question
Amplicon Length:   65
Reference Assays:   MYD88(dHsaIS2506945)
Restriction Enzymes:   HaeIII

Gene Information

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq Feb 2010]

Gene Symbol:   MYD88
Gene Name:   myeloid differentiation primary response gene (88)
Aliases:   MYD88D
RefSeq:   NC_000003.11 NG_023225.1 NT_022517.18 NG_016964.1
Ensembl:   ENSG00000172936
Entrez:   4615
UniGene:   Hs.82116
Chromosome Mapping:   3p22

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