This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for mutation detection. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: 77nt amplicon; crosses exon-intron junction; in silico
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors mast cell disease acute myelogenous lukemia and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]