PrimePCR™ ddPCR™ Mutation Assay:KRAS WT for p.Q61E, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for mutation detection. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   61nt amplicon; exonic; in silico

 
Fluorophore:   HEX
List Price:    $325.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Mutation Detection in silico design
Unique Assay ID:   dHsaIS2503955
Chromosome Location:   12:25380216-25380338question
Amplicon Length:   61
Restriction Enzymes:   HaeIII

Gene Information

This gene a Kirsten ras oncogene homolog from the mammalian ras gene family encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies including lung adenocarcinoma mucinous adenoma ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq Jul 2008]

Gene Symbol:   KRAS
Gene Name:   v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Aliases:   C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
RefSeq:   NC_000012.11 NG_007524.1 NT_009714.17
Ensembl:   ENSG00000133703
Entrez:   3845
UniGene:   Hs.505033
Chromosome Mapping:   12p12.1

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