PrimePCR™ ddPCR™ Mutation Assay:PIK3CA p.E453K, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for mutation detection. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   68nt amplicon; exonic; in silico

 
Fluorophore:   FAM
List Price:    $325.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Mutation Detection in silico design
Unique Assay ID:   dHsaIS2503846
Chromosome Location:   3:178928018-178928140question
Amplicon Length:   68
Reference Assays:   PIK3CA(dHsaIS2503847)
Restriction Enzymes:   MseI

Gene Information

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit which uses ATP to phosphorylate PtdIns PtdIns4P and PtdIns(45)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq Jul 2008]

Gene Symbol:   PIK3CA
Gene Name:   phosphoinositide-3-kinase, catalytic, alpha polypeptide
Aliases:   MGC142161, MGC142163, PI3K, p110-alpha
RefSeq:   NC_000003.11 NG_012113.1 NT_005612.16
Ensembl:   ENSG00000121879
Entrez:   5290
UniGene:   Hs.732403
Chromosome Mapping:   3q26.3

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