PrimePCR™ ddPCR™ Mutation Assay:MAP2K1 p.E203K, Human

PrimePCR

ddPCR probe assay designed for mutation detection. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   61nt amplicon; exonic; in silico

 
Fluorophore:   FAM
List Price:    $335.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Mutation Detection in silico design
Unique Assay ID:   dHsaIS2502804
Chromosome Location:   15:66774070-66774192question
Amplicon Length:   61
Reference Assays:  
Restriction Enzymes:   HaeIII

Gene Information

The protein encoded by this gene is a member of the dual specificity protein kinase family which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases also known as extracellular signal-regulated kinases (ERKs) act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway this kinase is involved in many cellular processes such as proliferation differentiation transcription regulation and development. [provided by RefSeq Jul 2008]

Gene Symbol:   MAP2K1
Gene Name:   mitogen-activated protein kinase kinase 1
Aliases:   MAPKK1, MEK1, MKK1, PRKMK1
RefSeq:   NC_000015.9 NG_008305.1 NT_010194.17
Ensembl:   ENSG00000169032
Entrez:   5604
UniGene:   Hs.145442
Chromosome Mapping:   15q22.1-q22.33

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