PrimePCR™ ddPCR™ Mutation Assay:H3F3A WT for p.G35R, Human


ddPCR probe assay designed for mutation detection. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   129nt amplicon; crosses exon-intron junction; in silico

Fluorophore:   HEX
List Price:    $335.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Mutation Detection in silico design
Unique Assay ID:   dHsaIS2502309
Chromosome Location:   1:226252094-226252216question
Amplicon Length:   129
Restriction Enzymes:   HaeIII

Gene Information

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A H2B H3 and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq Jul 2008]

Gene Symbol:   H3F3A
Gene Name:   H3 histone, family 3A
Aliases:   H3.3A, H3F3, H3F3B, MGC87782, MGC87783
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000163041
Entrez:   3020
UniGene:   Hs.533624
Chromosome Mapping:   1q41

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