PrimePCR™ ddPCR™ Expression EvaGreen® Assay: HIRA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0038913; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5190024
Chromosome Location:   22:19363275-19365475question
Amplicon Length:   95

Gene Information

This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast flies and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq Jul 2008]

Gene Symbol:   HIRA
Gene Name:   HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
Aliases:   DGCR1, TUP1, TUPLE1
RefSeq:   NC_000022.10 NG_009231.1 NT_011519.10
Ensembl:   ENSG00000100084
Entrez:   7290
UniGene:   Hs.474206
Chromosome Mapping:   22q11.2,22q11.21

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