PrimePCR™ ddPCR™ Expression EvaGreen® Assay: KIR2DL1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0038687; Intron-spanning

List Price:    $134.00
Your Price:   Log In

Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5190003
Chromosome Location:   19:55281317-55284873question
Amplicon Length:   115

Gene Information

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes although several "framework" genes are found in all haplotypes (KIR3DL3 KIR3DP1 KIR3DL4 KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM) while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq Jul 2008]

Gene Symbol:   KIR2DL1
Gene Name:   killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
Aliases:   CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1
RefSeq:   NC_000019.9 NG_005990.1 NG_005994.1 NT_011109.16
Ensembl:   ENSG00000125498
Entrez:   3802
UniGene:   Hs.654605
Chromosome Mapping:   19q13.4

Number Description Download