PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CACNB4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021708; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189762
Chromosome Location:   2:152727098-152728989question
Amplicon Length:   77

Gene Information

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1 alpha-2/delta beta and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition increasing peak calcium current controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Mar 2009]

Gene Symbol:   CACNB4
Gene Name:   calcium channel, voltage-dependent, beta 4 subunit
Aliases:   CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6
RefSeq:   NC_000002.11 NG_012641.1 NT_005403.17
Ensembl:   ENSG00000182389
Entrez:   785
UniGene:   Hs.120725
Chromosome Mapping:   2q22-q23

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