PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GLIS2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021223; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189740
Chromosome Location:   16:4385304-4386793question
Amplicon Length:   129

Gene Information

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP) an autosomal recessive kidney disease characterized by tubular basement membrane disruption interstitial lymphohistiocytic cell infiltration and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq Jan 2010]

Gene Symbol:   GLIS2
Gene Name:   GLIS family zinc finger 2
Aliases:   FLJ38247, NKL, NPHP7
RefSeq:   NC_000016.9 NG_016391.1 NT_010393.16
Ensembl:   ENSG00000126603
Entrez:   84662
UniGene:   Hs.592087
Chromosome Mapping:   16p13.3

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