PrimePCR™ ddPCR™ Expression EvaGreen® Assay: EDN3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015566; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189646
Chromosome Location:   20:57876691-57896115question
Amplicon Length:   101

Gene Information

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS) which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq Jul 2008]

Gene Symbol:   EDN3
Gene Name:   endothelin 3
Aliases:   ET3, HSCR4, MGC15067, MGC61498, WS4B
RefSeq:   NC_000020.10 NG_008050.1 NT_011362.10
Ensembl:   ENSG00000124205
Entrez:   1908
UniGene:   Hs.1408
Chromosome Mapping:   20q13.2-q13.3

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