PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GCK, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0014780; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189630
Chromosome Location:   7:44187367-44189572question
Amplicon Length:   140

Gene Information

Hexokinases phosphorylate glucose to produce glucose-6-phosphate the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM) maturity onset diabetes of the young type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq Apr 2009]

Gene Symbol:   GCK
Gene Name:   glucokinase (hexokinase 4)
Aliases:   FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, LGLK, MODY2
RefSeq:   NC_000007.13 NG_008847.1 NT_007819.17
Ensembl:   ENSG00000106633
Entrez:   2645
UniGene:   Hs.1270
Chromosome Mapping:   7p15.3-p15.1

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