PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PILRB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056491; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189391
Chromosome Location:   7:99965168-99965279question
Amplicon Length:   82

Gene Information

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the non-ITIM-bearing member of the receptor pair which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. Alternatively spliced transcript variants have been noted for this gene but the full-length nature of many is not known. [provided by RefSeq Aug 2010]

Gene Symbol:   PILRB
Gene Name:   paired immunoglobin-like type 2 receptor beta
Aliases:   FDFACT1, FDFACT2
RefSeq:   NC_000007.13 NT_007933.15
Ensembl:   ENSG00000121716
Entrez:   29990
UniGene:   Hs.632314
Chromosome Mapping:   7q22.1

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