PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CYP2A6, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048910; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189354
Chromosome Location:   19:41349536-41349627question
Amplicon Length:   62

Gene Information

This gene CYP2A6 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin and also metabolizes nicotine aflatoxin B1 nitrosamines and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however it has been renamed CYP2A6. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP2A6
Gene Name:   cytochrome P450, family 2, subfamily A, polypeptide 6
Aliases:   CPA6, CYP2A, CYP2A3, P450C2A, P450PB
RefSeq:   NC_000019.9 NG_000008.7 NG_008377.1 NT_011109.16
Ensembl:   ENSG00000255974
Entrez:   1548
UniGene:   Hs.250615
Chromosome Mapping:   19q13.2

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