PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FCGR3A, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048414; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189301
Chromosome Location:   1:161512777-161512890question
Amplicon Length:   84

Gene Information

This gene encodes a receptor for the Fc portion of immunoglobulin G and it is involved in the removal of antigen-antibody complexes from the circulation as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections susceptibility to systemic lupus erythematosus and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   FCGR3A
Gene Name:   Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Aliases:   CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
RefSeq:   NC_000001.10 NT_004487.19 NG_009066.1
Ensembl:   ENSG00000203747
Entrez:   2214
UniGene:   Hs.372679
Chromosome Mapping:   1q23

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