PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APITD1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0047098; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189227
Chromosome Location:   1:10490601-10493968question
Amplicon Length:   65

Gene Information

This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain similar to that found in TATA box-binding protein-associated factor TAF(II)31 which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors and was shown to reduce cell growth in neuroblastoma cells suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes including the Fanconi anemia (FA) core complex the APITD1/CENPS complex and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7. [provided by RefSeq Nov 2010]

Gene Symbol:   APITD1
Gene Name:   apoptosis-inducing, TAF9-like domain 1
Aliases:   CENP-S, CENPS, MGC32686, MHF1
RefSeq:   Not Available
Ensembl:   ENSG00000175279
Entrez:   378708
UniGene:   Not Available
Chromosome Mapping:   1p36.22

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