PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHRFAM7A, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046398; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5189191
Chromosome Location:   15:30654861-30659624question
Amplicon Length:   128

Gene Information

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7 which is located on chromosome 15 in a region associated with several neuropsychiatric disorders is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed and two variants exist for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq Jul 2008]

Gene Symbol:   CHRFAM7A
Gene Name:   CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
Aliases:   CHRNA7, CHRNA7-DR1, D-10, MGC120482, MGC120483
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000166664
Entrez:   89832
UniGene:   Hs.510853
Chromosome Mapping:   15q13.1

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