PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CKMT1B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038422; exonic

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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5188877
Chromosome Location:   15:43886418-43886562question
Amplicon Length:   115

Gene Information

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes sarcomeric MtCK and ubiquitous MtCK encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq Jul 2008]

Gene Symbol:   CKMT1B
Gene Name:   creatine kinase, mitochondrial 1B
Aliases:   CKMT, CKMT1, CKMT1A, UMTCK
RefSeq:   NC_000015.9 NG_005156.1 NG_011636.1 NG_022929.1 NT_010194.17
Ensembl:   ENSG00000237289
Entrez:   1159
UniGene:   Hs.425633
Chromosome Mapping:   15q15

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