PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CYP21A2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037455; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5188570
Chromosome Location:   6:32006913-32007147question
Amplicon Length:   97

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP21A2
Gene Name:   cytochrome P450, family 21, subfamily A, polypeptide 2
Aliases:   CA21H, CAH1, CPS1, CYP21, CYP21B, MGC150536, MGC150537, P450c21B
RefSeq:   NC_000006.11 NG_000013.3 NG_004658.2 NG_005163.2 NG_007941.2 NG_008337.1 NT_007592.15 NT_113891.2 NT_167245.1 NT_167247.1 NT_167249.1
Ensembl:   ENSG00000231852
Entrez:   1589
UniGene:   Hs.654479
Chromosome Mapping:   6p21.3

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