PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GCLC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0038628; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5025252
Chromosome Location:   6:53385585-53387257question
Amplicon Length:   189

Gene Information

Glutamate-cysteine ligase also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq Oct 2010]

Gene Symbol:   GCLC
Gene Name:   glutamate-cysteine ligase, catalytic subunit
Aliases:   GCL, GCS, GLCL, GLCLC
RefSeq:   NC_000006.11 NG_012071.1 NT_007592.15
Ensembl:   ENSG00000001084
Entrez:   2729
UniGene:   Hs.654465
Chromosome Mapping:   6p12

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