PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FDPS, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0038105; Intron-spanning

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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5025196
Chromosome Location:   1:155282150-155288013question
Amplicon Length:   142

Gene Information

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product farnesyl pyrophosphate is a key intermediate in cholesterol and sterol biosynthesis a substrate for protein farnesylation and geranylgeranylation and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1 7 14 15 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Oct 2008]

Gene Symbol:   FDPS
Gene Name:   farnesyl diphosphate synthase
Aliases:   FPPS, FPS
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000160752
Entrez:   2224
UniGene:   Hs.335918
Chromosome Mapping:   1q22

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