PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PTPN12, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0036511; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5024916
Chromosome Location:   7:77200454-77210797question
Amplicon Length:   74

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP contains a C-terminal PEST motif which serves as a protein-protein interaction domain and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with and dephosphorylate various products related to cytoskeletal structure and cell adhesion such as p130 (Cas) CAKbeta/PTK2B PSTPIP1 and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq Oct 2008]

Gene Symbol:   PTPN12
Gene Name:   protein tyrosine phosphatase, non-receptor type 12
Aliases:   PTP-PEST, PTPG1
RefSeq:   NC_000007.13 NT_007933.15 NG_008394.1
Ensembl:   ENSG00000127947
Entrez:   5782
UniGene:   Hs.61812
Chromosome Mapping:   7q11.23

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