PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CYP3A5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0036396; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5024883
Chromosome Location:   7:99272168-99277458question
Amplicon Length:   114

Gene Information

This geneCYP3A5 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene CYP3A5P1 which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq Jun 2010]

Gene Symbol:   CYP3A5
Gene Name:   cytochrome P450, family 3, subfamily A, polypeptide 5
Aliases:   CP35, CYPIIIA5, DKFZp686L16231, FLJ31317, P450PCN3, PCN3
RefSeq:   NC_000007.13 NG_000004.3 NG_007938.1 NT_007933.15
Ensembl:   ENSG00000106258
Entrez:   1577
UniGene:   Hs.571258
Chromosome Mapping:   7q21.1

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