PrimePCR™ ddPCR™ Expression EvaGreen® Assay: VDR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0023190; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5024671
Chromosome Location:   12:48251436-48272761question
Amplicon Length:   147

Gene Information

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq Feb 2011]

Gene Symbol:   VDR
Gene Name:   vitamin D (1,25- dihydroxyvitamin D3) receptor
Aliases:   NR1I1
RefSeq:   NC_000012.11 NT_029419.12 NG_008731.1
Ensembl:   ENSG00000111424
Entrez:   7421
UniGene:   Hs.524368
Chromosome Mapping:   12q13.11

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