PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MMP11, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0022136; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5024293
Chromosome Location:   22:24121519-24122629question
Amplicon Length:   139

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP11
Gene Name:   matrix metallopeptidase 11 (stromelysin 3)
Aliases:   SL-3, ST3, STMY3
RefSeq:   NC_000022.10 NG_009303.1 NT_011520.12
Ensembl:   ENSG00000099953
Entrez:   4320
UniGene:   Hs.143751
Chromosome Mapping:   22q11.2,22q11.23

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