PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CREBBP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021913; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5024222
Chromosome Location:   16:3786722-3788608question
Amplicon Length:   114

Gene Information

This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB) this gene is now known to play critical roles in embryonic development growth control and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain cysteine-histidine-rich regions and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq Feb 2009]

Gene Symbol:   CREBBP
Gene Name:   CREB binding protein
Aliases:   CBP, KAT3A, RSTS
RefSeq:   NC_000016.9 NT_010393.16 NG_009873.1
Ensembl:   ENSG00000005339
Entrez:   1387
UniGene:   Hs.459759
Chromosome Mapping:   16p13.3

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