PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PTK2B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021171; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5023815
Chromosome Location:   8:27255282-27277541question
Amplicon Length:   124

Gene Information

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration nicotinic acetylcholine receptor activation membrane depolarization or protein kinase C activation. This protein has been shown to bind CRK-associated substrate nephrocystin GTPase regulator associated with FAK and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PTK2B
Gene Name:   PTK2B protein tyrosine kinase 2 beta
Aliases:   CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK
RefSeq:   NC_000008.10 NG_015827.1 NT_167187.1
Ensembl:   ENSG00000120899
Entrez:   2185
UniGene:   Hs.491322
Chromosome Mapping:   8p21.1

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