PrimePCR™ ddPCR™ Expression EvaGreen® Assay: UPF1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0020860; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5023624
Chromosome Location:   19:18974370-18976128question
Amplicon Length:   135

Gene Information

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   UPF1
Gene Name:   UPF1 regulator of nonsense transcripts homolog (yeast)
Aliases:   FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, RENT1, pNORF1
RefSeq:   NC_000019.9 NG_012070.1 NT_011295.11
Ensembl:   ENSG00000005007
Entrez:   5976
UniGene:   Hs.515266
Chromosome Mapping:   19p13.2-p13.11

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