PrimePCR™ ddPCR™ Expression EvaGreen® Assay: UBB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0020639; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5023575
Chromosome Location:   17:16284418-16285247question
Amplicon Length:   83

Gene Information

This gene encodes ubiquitin one of the most conserved proteins known. Ubiquitin is required for ATP-dependent nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq Jul 2008]

Gene Symbol:   UBB
Gene Name:   ubiquitin B
Aliases:   FLJ25987, MGC8385, RPS27A, UBA52, UBC
RefSeq:   NC_000017.10 NG_023320.1 NT_010718.16
Ensembl:   ENSG00000170315
Entrez:   7314
UniGene:   Hs.356190
Chromosome Mapping:   17p12-p11.2

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