PrimePCR™ ddPCR™ Expression EvaGreen® Assay: HAMP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0020626; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5023572
Chromosome Location:   19:35773528-35775922question
Amplicon Length:   155

Gene Information

The product encoded by this gene is involved in the maintenance of iron homeostasis and it is necessary for the regulation of iron storage in macrophages and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20 22 and 25 amino acids and these active peptides are rich in cysteines which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B also known as juvenile hemochromatosis a disease caused by severe iron overload that results in cardiomyopathy cirrhosis and endocrine failure. [provided by RefSeq Jul 2008]

Gene Symbol:   HAMP
Gene Name:   hepcidin antimicrobial peptide
Aliases:   HEPC, HFE2B, LEAP1, PLTR
RefSeq:   NC_000019.9 NG_011563.1 NT_011109.16
Ensembl:   ENSG00000105697
Entrez:   57817
UniGene:   Hs.731581
Chromosome Mapping:   19q13.1

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