PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DRAP1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0020609; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5023566
Chromosome Location:   11:65687251-65687462question
Amplicon Length:   87

Gene Information

Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA TFIIB and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq Jul 2008]

Gene Symbol:   DRAP1
Gene Name:   DR1-associated protein 1 (negative cofactor 2 alpha)
Aliases:   NC2-alpha
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000175550
Entrez:   10589
UniGene:   Hs.356742
Chromosome Mapping:   11q13.3

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