PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CASP4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0018365; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5023199
Chromosome Location:   11:104820402-104821721question
Amplicon Length:   143

Gene Information

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein as well as caspase 1 precursor. When overexpressed this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   CASP4
Gene Name:   caspase 4, apoptosis-related cysteine peptidase
Aliases:   ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000196954
Entrez:   837
UniGene:   Hs.138378
Chromosome Mapping:   11q22.2-q22.3

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