PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TGFB2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0018360; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5023195
Chromosome Location:   1:218610773-218614648question
Amplicon Length:   139

Gene Information

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines which are multifunctional peptides that regulate proliferation differentiation adhesion migration and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental including cardiac defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Sep 2010]

Gene Symbol:   TGFB2
Gene Name:   transforming growth factor, beta 2
Aliases:   MGC116892, TGF-beta2
RefSeq:   NC_000001.10 NG_027721.1 NT_167186.1
Ensembl:   ENSG00000092969
Entrez:   7042
UniGene:   Hs.133379
Chromosome Mapping:   1q41

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