PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DNMT3L, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0018059; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022980
Chromosome Location:   21:45674569-45678445question
Amplicon Length:   118

Gene Information

CpG methylation is an epigenetic modification that is important for embryonic development imprinting and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   DNMT3L
Gene Name:   DNA (cytosine-5-)-methyltransferase 3-like
Aliases:   MGC1090
RefSeq:   NC_000021.8 NT_011515.12
Ensembl:   ENSG00000142182
Entrez:   29947
UniGene:   Hs.592165
Chromosome Mapping:   21q22.3

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